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Endometrial Scoring for Prediction of Implantation Evaluation of Drug Therapy
Jaideep Malhotra (Doctor)
Narendra Malhotra (Doctor)
Jatin P. Shah
Pranay Shah
Vanaj Mathur
Meena, Shobhna, Sarika, Abanesh
B. Singh
Malhotra Test Tube Baby Centre,
Malhotra Ultrasound Imaging Centre,
Agra, India
Summary
- The present paper describes the authors' experience of uterine scoring in the prediction of implantation, as well as an investigation into the effects of the non-hormonal, non-steroidal, Ayurvedic medicine M2-TONE on pregnancy rates with assisted reproductive technologies (ART).
- The results indicate that a 'perfect' uterine score can successfully predict implantation (and hence pregnancy) in 75-85% of spontan-eous (natural) and induced cycles.
- Adjunctive therapy with M2-TONE, alone or in combination with aspirin or glyceryl trinitrate (GTN), appeared to enhance uterine score and, consequently, clinical pregnancy rates with ART.
- The future will see a marked increase in pregnancy and 'take-home baby rates' with advances in blastocyst transfer technologies and uterine scoring for the prediction of implantation.
Editor's Comment
Although advances in ART have substantially increased the success of infertility treatment, there appears to be no standard protocol or central monitoring body observing outcomes. In this article, the key issue of identifying which individuals are most receptive to implantation is investigated; hopefully, it will help in standardising patient selection for in vitro fertilisation with embryo transfer (IVF-ET).
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