Toxoplasmosis in Pregnancy: A Review

Key Points

• Toxoplasmosis in pregnancy can cause significant morbidity to the offspring.
  
  
• Prevention can be effective if those at risk are taught how to avoid infection, an important aspect of health education.
  
  
• Drug treatment is effective in limiting the impact of this disease and should be commenced as soon as possible after the diagnosis is made.

Editor's Comment

Toxoplasmosis, a zoonotic infection, is caused by Toxoplasma gondii. Acute infection is usually followed by a chronic, asymptomatic state. However, in the obstetric setting T. gondii can cause severe ophthalmological and/or neurological disease, congenital malformations or even death in the developing foetus. The grim consequences of toxoplasmosis necessitate vigilance in diagnosis and active management.

Clinical Evaluation of M2-TONE in Unexplained Infertility

Dr. Chandravati (Head)
Dr. Manju Shukla

Department of Obstetrics and Gynaecology,
King Georges Medical College, Lucknow, India

Summary

• The present (uncontrolled) study assessed the efficacy of M2-TONE syrup ('M2-TONE'), a comprehensive non-hormonal herbomineral formulation, in the treatment of 165 women with unexplained infertility.
  
  
• The overall conception rate on M2-TONE was very good (33%); there were no side effects of treatment.
  
  
• Menstrual irregularities associated with unexplained infertility were also improved by M2-TONE.
  
  
• M2-TONE is a valuable alternative therapy in the gynaecological armamentarium for the treatment of unexplained infertility.

Editor's Comment

Although the beneficial effects of numerous herbal/ayurvedic preparations in various gynaecological disorders have long been known, they have not to date been scientifically rationalised. In the present (uncontrolled) study, one such preparation (M2-TONE) was assessed in the treatment of unexplained infertility. The results are certainly encouraging, but need to be confirmed under controlled conditions.

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