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Successful Pregnancy in NOA Infertility Using ICSI

M. K. H. Leong (Doctor)*
K. K. Wong (Surgeon)**
C. K. M. Leung (Doctor)*
C. Wong
W. Tang
F. Tang

IVF Centre (Department of Obstetrics and Gynaecology*;
Department of Surgery**), Hong Kong Sanatorium and
Hospital, Hong Kong, China

 

Summary

  • Using a combination of testicular sperm extraction (TESE), intracytoplasmic sperm injection (ICSI), and micromanipulation followed by immediate fallopian tube transfer (MIFT), two pregnancies were attempted in a couple where the husband had non-obstructive azoospermia (NOA).

  • The first pregnancy resulted in spontaneous abortion, but the second resulted in the delivery of a healthy baby boy.

  • Testicular sperm retrieval and assisted reproduction techniques now offer such couples the opportunity to conceive their own offspring.

  • Cryopreservation of sperm-bearing testicular biopsies enables multiple ICSI cycles without the need for additional sperm retrieval procedures.

 

Editor's Comment

With the advent of ICSI, NOA is no longer an untreatable cause of infertility. The methodology used to achieve a successful pregnancy with this technique, along with a brief discussion of the procedure's merits is outlined in the current paper, modified and reprinted with kind permission from the Hong Kong Medical Journal (1999;5:69-71).



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