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Hormonal Replacement Therapy (HRT)

Key Points

• HRT (oestrogen plus progestin) has a beneficial effect on bone preservation, the lipid profile, and the cardiovascular system in previously healthy women.
  
  
• Unopposed oestrogen should not be used in women with an intact uterus.
  
  
• HRT is not recommended for secondary prevention of CHD.
  
  
• There is an increased risk of thromboembolic complications with HRT, but the risk-benefit profile is unchanged for most women.

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